Internal Medicine MCQs Posted by Dr Vinod Date September 1, 2025 Comments 0 comment Welcome to your Internal Medicine MCQs Name Email Phone 1. Which of the following is NOT a feature of nephrotic syndrome ? Hematuria Hypoalbuminemia Edema Hyperlipidemia None 2. Which of the following is not part of the Glasgow Coma Scale ? Verbal response Motor response Eye opening Pupillary reaction None 3. Which of the following viruses is transmissible even after medical instrumentation is cleaned with alcohol ? HIV Herpes simplex Epstein-Barr virus Adenovirus None 4. Which of the following is true regarding initial therapy for type 2 diabetes mellitus(except renal failure patients) ? Start with insulin for all Start with sulfonylurea for all Start with metformin Start with SGLT2 inhibitor None 5. Which of the following does NOT cause fever of unknown origin (FUO) ? Simple viral pharyngitis Tuberculosis Rheumatoid arthritis Lymphoma None 6. The best initial management for acute gout is ? Corticosteroids Colchicine Allopurinol NSAIDs None 7. Which ECG finding is most specific for acute pericarditis ? U waves Diffuse ST elevation T wave inversion Q waves None 8. A 55-year-old man presents with polyuria, polydipsia, and weight loss. Lab findings show hyperglycemia and glycosuria. The most likely diagnosis is ? Type 2 diabetes mellitus Diabetes insipidus Type 1 diabetes mellitus Cushing’s syndrome None 9. Which test is best for evaluating unexplained fever in the hospital setting ? Urinalysis All of the above Blood culture Chest X-ray None 10. What is the main mechanism for fasting hyperglycemia in type 2 diabetes ? Compensatory hyperinsulinemia Decreased peripheral glucose uptake Increased hepatic glucose production Impaired insulin secretion None 11. Which of the following is required to confirm the diagnosis of diabetes mellitus? 2-hour glucose during OGTT ≥200 mg/dL All of the above HbA1c ≥6.5% Fasting plasma glucose ≥126 mg/dL None 12. The best screening test for colorectal cancer is ? Colonoscopy Barium enema CT scan Fecal occult blood test None 13. A 35-year-old female presents with acute onset of unilateral facial paralysis. She is unable to close her right eye. What is the most likely diagnosis ? Cluster headache Bell’s palsy Myasthenia gravis Stroke None 14. The most common cause of acute pancreatitis is ? Hypercalcemia Viral infection Gallstones Alcohol None 15. Which of the following is NOT used to treat tuberculosis ? Isoniazid Pyrazinamide Ivermectin Rifampin None 16. The drug of choice for status epilepticus is ? Phenytoin Carbamazepine Diazepam Valproate None 17. In patients with atrial fibrillation, the most important reason for anticoagulation is prevention of ? Bleeding Heart failure Renal failure Stroke None 18. The most sensitive investigation for detecting intracranial hemorrhage acutely is ? CT scan EEG MRI Lumbar puncture None 19. All of the following are classic symptoms of myocardial infarction EXCEPT ? Chest pain Diaphoresis Shortness of breath Polyuria None 20. The initial treatment of hyperkalemia with ECG changes is ? Furosemide IV calcium gluconate Sodium bicarbonate Sodium polystyrene sulfonate None 21. Which of the following is NOT a risk factor for coronary artery disease ? Hypertension Hypothyroidism Smoking Hyperlipidemia None 22. The first-line treatment for hypertension in a diabetic patient with proteinuria is ? Thiazide diuretic ACE inhibitor Calcium channel blocker Beta-blocker None 23. The earliest sign of papilledema due to raised intracranial pressure is ? Sixth nerve palsy Papilledema Loss of optic cup Visual obscurations None 24. Which of the following is a late complication of myocardial infarction ? Heart block Arrhythmia Dressler’s syndrome Pericarditis None 25. The classic symptom triad of diabetic ketoacidosis (DKA) includes ? Fever, joint pain, rash Polyuria, polydipsia, and weight loss Confusion, blurred vision, cough Nausea, vomiting, constipation None 26. A 40-year-old woman presents with chronic diarrhea and a serum anti-tissue transglutaminase antibody. Diagnosis is ? Ulcerative colitis Celiac disease Crohn’s disease Irritable bowel syndrome None 27. In a hospitalized patient with a new fever and Systemic Inflammatory Response Syndrome (SIRS) criteria, which of the following tests is most commonly ordered first? Liver function tests Serum ferritin Blood cultures Cardiac enzymes None 28. Which of the following is the most common cause of community-acquired pneumonia in adults? Staphylococcus aureus Streptococcus pneumoniae Haemophilus influenzae Mycoplasma pneumoniae None 29. Which of the following is the most common cause of persistent fever with chills in a patient from India ? Tuberculosis Enteric fever Leptospirosis Malaria None 30. Which electrolyte imbalance is most commonly associated with digoxin toxicity? Hypercalcemia Hypokalemia Hyperkalemia Hypocalcemia None Share: Dr Vinod Previous post Critical Care MCQs September 1, 2025 Next post Fellowship in Pediatrics October 7, 2025 You may also like Is Working in a Tier 2 City Actually Better for Indian Doctors in 2026? July 28, 2026 India’s ICU Capacity Crisis : What It Means for Doctors and Patients in 2026 July 27, 2026 Fellowship Courses Without NEET PG: A credible career path for MBBS doctors January 22, 2026
