Internal Medicine MCQs Posted by Pujari Vinod Date September 1, 2025 Comments 0 comment Welcome to your Internal Medicine MCQs Name Email Phone 1. Which of the following is characteristic of infective endocarditis ? New murmur Cough Hemoptysis Chest pain None 2. The most sensitive investigation for detecting intracranial hemorrhage acutely is ? EEG MRI Lumbar puncture CT scan None 3. Which ECG finding is most specific for acute pericarditis ? Diffuse ST elevation T wave inversion Q waves U waves None 4. Which of the following is the most common cause of persistent fever with chills in a patient from India ? Tuberculosis Leptospirosis Enteric fever Malaria None 5. A patient with chronic liver disease is most likely to die from ? Renal failure Infection GI hemorrhage Liver failure None 6. In a hospitalized patient with a new fever and Systemic Inflammatory Response Syndrome (SIRS) criteria, which of the following tests is most commonly ordered first? Serum ferritin Cardiac enzymes Liver function tests Blood cultures None 7. The most common cause of acute pancreatitis is ? Gallstones Hypercalcemia Alcohol Viral infection None 8. A patient presents with fever, malaise, and a rash. Lab examination reveals a negative Monospot test and atypical lymphocytes. Which is the most likely diagnosis ? Infectious mononucleosis Scarlet fever Acute HIV infection Cytomegalovirus infection None 9. Which of the following is NOT a feature of nephrotic syndrome ? Hypoalbuminemia Hematuria Edema Hyperlipidemia None 10. In patients with atrial fibrillation, the most important reason for anticoagulation is prevention of ? Heart failure Renal failure Stroke Bleeding None 11. The classic symptom triad of diabetic ketoacidosis (DKA) includes ? Nausea, vomiting, constipation Fever, joint pain, rash Confusion, blurred vision, cough Polyuria, polydipsia, and weight loss None 12. Which is the most sensitive test for early diabetic nephropathy ? Ultrasound Serum creatinine Microalbuminuria 24-hour urine protein None 13. Which is an absolute contraindication to thrombolytic therapy ? Non-STEMI Recent surgery Severe hypertension Allergy to aspirin None 14. Which ECG change is considered highly specific for acute pericarditis ? QT prolongation ST elevation (diffuse) PR depression QRS widening None 15. Which clinical finding is most associated with suspected hypertensive emergency ? BP 160/90 mmHg in a young adult BP 130/85 mmHg with mild ankle edema BP 180/105 mmHg with headache BP 200/120 mmHg with papilledema and confusion None 16. Which of the following is a late complication of myocardial infarction ? Pericarditis Heart block Dressler’s syndrome Arrhythmia None 17. Which electrolyte imbalance is most commonly associated with digoxin toxicity? Hypocalcemia Hypercalcemia Hypokalemia Hyperkalemia None 18. Which of the following is NOT a risk factor for coronary artery disease ? Smoking Hyperlipidemia Hypothyroidism Hypertension None 19. Which test is best for evaluating unexplained fever in the hospital setting ? All of the above Chest X-ray Blood culture Urinalysis None 20. Which of the following is true regarding initial therapy for type 2 diabetes mellitus(except renal failure patients) ? Start with insulin for all Start with metformin Start with sulfonylurea for all Start with SGLT2 inhibitor None 21. Which of the following is NOT used to treat tuberculosis ? Isoniazid Rifampin Pyrazinamide Ivermectin None 22. Which of the following features most reliably distinguishes asthma from COPD? Wheezing Chest tightness Reversibility with bronchodilators Productive cough None 23. The best initial management for acute gout is ? Colchicine Allopurinol NSAIDs Corticosteroids None 24. The initial treatment of hyperkalemia with ECG changes is ? Sodium bicarbonate Furosemide Sodium polystyrene sulfonate IV calcium gluconate None 25. A 68-year-old woman with diabetes and hypertension has a blood pressure of 150/90 mmHg. What is the most appropriate antihypertensive to start? Bisoprolol Amlodipine Ramipril Hydrochlorothiazide None 26. Which investigation is most useful for confirming deep vein thrombosis ? D-dimer CT scan Ultrasound Doppler Venography None 27. Which of the following is not part of the Glasgow Coma Scale ? Eye opening Pupillary reaction Motor response Verbal response None 28. Which of the following antihypertensive agents is contraindicated in pregnancy ? Labetalol ACE inhibitors Methyldopa Hydralazine None 29. The drug of choice for status epilepticus is ? Valproate Phenytoin Carbamazepine Diazepam None 30. Which of the following is required to confirm the diagnosis of diabetes mellitus? Fasting plasma glucose ≥126 mg/dL 2-hour glucose during OGTT ≥200 mg/dL All of the above HbA1c ≥6.5% None Share: Pujari Vinod Previous post Critical Care MCQs September 1, 2025 Next post Fellowship in Pediatrics October 7, 2025 You may also like Fellowship Courses After MBBS in India: A Practical Career Guide December 26, 2025 Top International Certification Programs for Indian Doctors June 5, 2025 Career Options for Doctors After MBBS in India June 5, 2025
