Internal Medicine MCQs Posted by Pujari Vinod Date September 1, 2025 Comments 0 comment Welcome to your Internal Medicine MCQs Name Email Phone 1. Which of the following is a late complication of myocardial infarction ? Arrhythmia Pericarditis Dressler’s syndrome Heart block None 2. In patients with atrial fibrillation, the most important reason for anticoagulation is prevention of ? Renal failure Heart failure Stroke Bleeding None 3. In a patient with acute MI, the earliest ECG change is ? Tall T waves T wave inversion ST elevation Pathological Q waves None 4. A 6-year-old boy presents with periorbital edema and frothy urine. The most likely diagnosis is ? Nephrotic syndrome Renal tubular acidosis Urinary tract infection Acute glomerulonephritis None 5. The drug of choice for status epilepticus is ? Phenytoin Carbamazepine Valproate Diazepam None 6. A 72-year-old woman has new-onset atrial flutter and is hemodynamically stable. The best IV drug to control her heart rate is ? Magnesium Lidocaine Aminophylline Diltiazem None 7. Which of the following antibiotics is most appropriate for treating a life-threatening Methicillin-Resistant Staphylococcus aureus infection ? Gentamicin Penicillin Erythromycin Vancomycin None 8. Which of the following antihypertensive agents is contraindicated in pregnancy ? Methyldopa ACE inhibitors Labetalol Hydralazine None 9. Which of the following viruses is transmissible even after medical instrumentation is cleaned with alcohol ? Epstein-Barr virus Herpes simplex Adenovirus HIV None 10. The initial treatment of hyperkalemia with ECG changes is ? IV calcium gluconate Sodium polystyrene sulfonate Sodium bicarbonate Furosemide None 11. A 68-year-old woman with diabetes and hypertension has a blood pressure of 150/90 mmHg. What is the most appropriate antihypertensive to start? Amlodipine Bisoprolol Ramipril Hydrochlorothiazide None 12. A 40-year-old woman presents with chronic diarrhea and a serum anti-tissue transglutaminase antibody. Diagnosis is ? Celiac disease Crohn’s disease Irritable bowel syndrome Ulcerative colitis None 13. Which of the following is true regarding initial therapy for type 2 diabetes mellitus(except renal failure patients) ? Start with metformin Start with SGLT2 inhibitor Start with sulfonylurea for all Start with insulin for all None 14. All of the following are classic symptoms of myocardial infarction EXCEPT ? Shortness of breath Diaphoresis Polyuria Chest pain None 15. In a hospitalized patient with a new fever and Systemic Inflammatory Response Syndrome (SIRS) criteria, which of the following tests is most commonly ordered first? Liver function tests Blood cultures Cardiac enzymes Serum ferritin None 16. Which of the following does NOT cause fever of unknown origin (FUO) ? Lymphoma Tuberculosis Simple viral pharyngitis Rheumatoid arthritis None 17. Which one of the following is NOT a recognized complication of myocardial infarction ? Arrhythmias Left ventricular aneurysm Diabetes insipidus Pericarditis None 18. Which investigation is most useful for confirming deep vein thrombosis ? CT scan Ultrasound Doppler D-dimer Venography None 19. Which electrolyte imbalance is most commonly associated with digoxin toxicity? Hypocalcemia Hyperkalemia Hypercalcemia Hypokalemia None 20. Which of the following is required to confirm the diagnosis of diabetes mellitus? HbA1c ≥6.5% 2-hour glucose during OGTT ≥200 mg/dL Fasting plasma glucose ≥126 mg/dL All of the above None 21. The earliest sign of papilledema due to raised intracranial pressure is ? Sixth nerve palsy Papilledema Loss of optic cup Visual obscurations None 22. Which ECG finding is most specific for acute pericarditis ? Q waves Diffuse ST elevation T wave inversion U waves None 23. A 35-year-old female presents with acute onset of unilateral facial paralysis. She is unable to close her right eye. What is the most likely diagnosis ? Bell’s palsy Stroke Myasthenia gravis Cluster headache None 24. Which of the following is not part of the Glasgow Coma Scale ? Eye opening Pupillary reaction Verbal response Motor response None 25. A patient with chronic liver disease is most likely to die from ? Renal failure Infection Liver failure GI hemorrhage None 26. Which test is best for evaluating unexplained fever in the hospital setting ? All of the above Urinalysis Blood culture Chest X-ray None 27. The first-line treatment for hypertension in a diabetic patient with proteinuria is ? ACE inhibitor Thiazide diuretic Calcium channel blocker Beta-blocker None 28. Which of the following is NOT a feature of nephrotic syndrome ? Edema Hypoalbuminemia Hyperlipidemia Hematuria None 29. The best screening test for colorectal cancer is ? CT scan Colonoscopy Fecal occult blood test Barium enema None 30. A patient presents with fever, malaise, and a rash. Lab examination reveals a negative Monospot test and atypical lymphocytes. Which is the most likely diagnosis ? Scarlet fever Infectious mononucleosis Acute HIV infection Cytomegalovirus infection None Share: Pujari Vinod Previous post Critical Care MCQs September 1, 2025 Next post Fellowship in Pediatrics October 7, 2025 You may also like Fellowship Courses Without NEET PG: A credible career path for MBBS doctors January 22, 2026 Fellowship Courses After MBBS in India: A Practical Career Guide December 26, 2025 Top International Certification Programs for Indian Doctors June 5, 2025
